Treatment of Stage II Soft Tissue Sarcoma and Stage III Soft Tissue Sarcoma That Has Not Spread to Lymph Nodes

For information about the treatments listed below, see Treatment Option Overview. To learn about the cancer stages, see Stages of Soft Tissue Sarcoma.

Treatment of stage II soft tissue sarcoma and stage III soft tissue sarcoma that has not spread to lymph nodes may include the following:

• Surgery to remove the tumor, such as wide local excision or limb-sparing surgery.
• Radiation therapy before or after surgery.
• Radiation therapy and/or chemotherapy before limb-sparing surgery. Radiation therapy may also be given after surgery.
• High-dose radiation therapy for tumors that cannot be removed by surgery.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.